Variant position: 101 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 524 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human WAEEETVA-----------AAQLITMLWSLS VSSFAVGGMTASFFGGWLGDT
Mouse WDEEETEG-----------SAHIVTMLWSLS VSSFAVGGMV
Rat W-EEETEG-----------SAHIVTMLWSLS VSSFAVGGMV
Pig WAEEETTA-----------SASLIIMLWSLS VSIFAIGGMI
Bovine WAEEETMT-----------SASLITMFWSLS VSSFAVGGMI
Chicken WGSSEGTLAPSAGFEDPTVSPHILTMYWSLS VSMFAVGGMV
Baker's yeast YLESTSNP-----------SLEHFSTLIDLA VMELP--GQL
Fission yeast FLESTSKL-----------TQDHISSFIDFS VWDFP--GQV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 524 Solute carrier family 2, facilitated glucose transporter member 2
99 – 119 Helical; Name=2
1 – 123 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLG -> MHLN. In isoform 2.
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.