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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P43657: Variant p.Cys137Trp

Lysophosphatidic acid receptor 6
Gene: LPAR6
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Variant information Variant position: help 137
Type of variant: help LB/B
Residue change: help From Cysteine (C) to Tryptophan (W) at position 137 (C137W, p.Cys137Trp).
Physico-chemical properties: help Change from medium size and polar (C) to large size and aromatic (W)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 137
Protein sequence length: help 344
Location on the sequence: help AIVYPFKSKTLRTKRNAKIV C TGVWLTVIGGSAPAVFVQST
Residue conservation: help
Human                         AIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQST

Mouse                         AIVYPFKSKTLRTKRNAKIVCIAVWFTVMGGSAPAVFFQST

Rat                           AIVYPFKSKTLRTKRNAKIVCIAVWFTVMGGSAPAVFFQST

Chicken                       AIVHPFRSKTLRTKRNARIVCVAVWITVLAGSTPASFFQST

Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 344 Lysophosphatidic acid receptor 6
Transmembrane 134 – 154 Helical; Name=4
Disulfide bond 89 – 168



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANT TRP-137;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.