Variant position: 174 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 472 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VQMILNSLINKSKSSMFQVR TLRELLWGYRDPFLSLVPYPV
Mouse VQVVLNSLIKKSKSSMFQTR SLKELLWGYKDPFLSLVPYPI
Rat VQGVLNSLIKKSKSSMFQTR SLKELLWGYKDPFLSLVPYPI
Bovine MQGILNSFIKKSKSSMFQNR TLKELLWGYTDPFLNLVPYPI
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 472 Platelet glycoprotein 4
30 – 439 Extracellular
163 – 163 N-linked (GlcNAc...) asparagine
144 – 203 Missing. In isoform 4.
169 – 174
Variability of the CD36 gene in West Africa.
Gelhaus A.; Scheding A.; Browne E.; Burchard G.D.; Horstmann R.D.;
Hum. Mutat. 18:444-450(2001)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-203; 274-375 AND 419-472; VARIANTS LYS-123; ALA-174; ASN-232 INS AND THR-271;
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.