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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P22680: Variant p.Asn233Ser

Cytochrome P450 7A1
Gene: CYP7A1
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Variant information Variant position: help 233
Type of variant: help LB/B
Residue change: help From Asparagine (N) to Serine (S) at position 233 (N233S, p.Asn233Ser).
Physico-chemical properties: help Change from medium size and polar (N) to small size and polar (S)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 233
Protein sequence length: help 504
Location on the sequence: help DKVFPALVAGLPIHMFRTAH N AREKLAESLRHENLQKRESI
Residue conservation: help 
Human                         DKVFPALVAGLPIHMFRTAHNAREKLAESLRHENLQKRESI

Mouse                         DQVFPALVAGVPIHLFKTAHKARERLAESLKHKNLYMRDQV

Rat                           DQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQV

Pig                           DKIFPALVAGFPIHVFKTGHYAREKLAEGLRLQKLRKRDHI

Rabbit                        DKVFPALVAGLPIHIFMTAHNAREKLAEGLKHDNLRTRDHI
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 504 Cytochrome P450 7A1
Helix 229 – 241



Literature citations
Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population.
Saito S.; Iida A.; Sekine A.; Kawauchi S.; Higuchi S.; Ogawa C.; Nakamura Y.;
J. Hum. Genet. 48:249-270(2003)
Cited for: VARIANTS SER-233 AND ASN-347;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.