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UniProtKB/Swiss-Prot Q99973: Variant p.Ser1447Thr

Telomerase protein component 1
Gene: TEP1
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Variant information Variant position: help 1447
Type of variant: help LB/B
Residue change: help From Serine (S) to Threonine (T) at position 1447 (S1447T, p.Ser1447Thr).
Physico-chemical properties: help Change from small size and polar (S) to medium size and polar (T)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 1447
Protein sequence length: help 2627
Location on the sequence: help TVDQLHGVLSVWRTLPKGTK S WEEAVAAGNSGDPYPMGPFA
Residue conservation: help 
Human                         TVDQLHGVLSVWRTLPKGTKSWEEAVAAGNSGDPYPMGPFA

Mouse                         TVDQLHAILSTWLILPKETKSWEEVLAASHSGNPFPLCPFA

Rat                           TVDQLHAVLSTWLTLPKETKSWEEAVAASHSGNLYPLAPFA

Baker's yeast                 IT-------------------------------------VA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 2627 Telomerase protein component 1
Domain 1162 – 1490 NACHT
Repeat 1411 – 1448 WD 1



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.