UniProtKB/SwissProt variant VAR

Triggering receptor expressed on myeloid cells 1
Gene: TREM1
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Variant information Variant position:

25
Type of variant:

LB/B
Residue change:

From Threonine (T) to Serine (S) at position 25 (T25S, p.Thr25Ser).
Physico-chemical properties:

Change from medium size and polar (T) to small size and polar (S)
BLOSUM score:

1
Other resources:

Variant rs2234237 [ dbSNP | Ensembl ]

Sequence information Variant position:

25
Protein sequence length:

234
Location on the sequence:

RLWGLLWMLFVSELRAATKL T EEKYELKEGQTLDVKCDYTL
Residue conservation:

Human                         RLWGLLWMLFVSELRAATKLTEEKYELKEGQTLDVKCDYTL

Mouse                         GLWGLLCVFFVSEVKAAIVLEEERYDLVEGQTLTVKCPFNI

Pig                           RLGRLLWMLFITEIQAATELPEEKYILAEGETLNVNCPVTV

Bovine                        GVWGLLWMLFIEEIQAAAEVFEEKCTLAEGQTLKVSCPTNT

Sequence annotation in neighborhood:

Type	Positions	Description
Chain	21 – 234	Triggering receptor expressed on myeloid cells 1
Topological domain	21 – 205	Extracellular
Beta strand	22 – 30

Literature citations
Submission
Suzuki Y.; Sugano S.; Totoki Y.; Toyoda A.; Takeda T.; Sakaki Y.; Tanaka A.; Yokoyama S.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-200; VARIANT SER-25;

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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9NP99: Variant p.Thr25Ser