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UniProtKB/Swiss-Prot Q99741: Variant p.Arg378His

Cell division control protein 6 homolog
Gene: CDC6
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Variant information Variant position: help 378
Type of variant: help LB/B
Residue change: help From Arginine (R) to Histidine (H) at position 378 (R378H, p.Arg378His).
Physico-chemical properties: help Change from large size and basic (R) to medium size and polar (H)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 378
Protein sequence length: help 560
Location on the sequence: help RLNQVSRDQVLDNAAVQFCA R KVSAVSGDVRKALDVCRRAI
Residue conservation: help 
Human                         RLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAI

Mouse                         RLSQVSKDQVLDSAAIQFCARKVSAVSGDIRKALDVCRRAI

Baker's yeast                 KMSSLP-TIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSI
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 560 Cell division control protein 6 homolog



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS ALA-238; ASN-295; MET-299; HIS-378 AND ILE-441;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.