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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q08050: Variant p.Ser643Pro

Forkhead box protein M1
Gene: FOXM1
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Variant information Variant position: help 643
Type of variant: help LB/B
Residue change: help From Serine (S) to Proline (P) at position 643 (S643P, p.Ser643Pro).
Physico-chemical properties: help Change from small size and polar (S) to medium size and hydrophobic (P)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 643
Protein sequence length: help 763
Location on the sequence: help SWRLTPPAKVGGLDFSPVQT S QGASDPLPDPLGLMDLSTTP
Residue conservation: help 
Human                         SWRL-TPPAKVGGLDFSPVQTSQGA-SDPLPDPLGLMDLSTTP

Mouse                         SWRL-TPPAKVGGLDFSPVRTPQGA-FGLLPDSLGLMELNT

Rat                           SWRL-TPPAKVGGLDFSPVRTPQGA-FGPLPDSLGLMELNT

Xenopus laevis                PWESETSLPRDPVLDFSPVRIPQGSTFTPFKDNLGTLSFGD
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 763 Forkhead box protein M1
Region 482 – 711 Disordered
Modified residue 627 – 627 Phosphothreonine
Modified residue 662 – 662 Phosphothreonine



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS GLU-402; LEU-450; PRO-643; ARG-669 AND LEU-673; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2); VARIANT PRO-643;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.