Variant position: 609 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 669 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SAEGDVGDGDGDFGAGVNKD GGSRVVVQMEEVARTVNVVMV
Mouse GDSKEENAGD--------KD EGSRVVVQMEEVVRTVNVVMV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
132 – 669 Matrix metalloproteinase-15
132 – 625 Extracellular
589 – 589 Phosphoserine
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS PRO-200; LEU-350; GLY-596; ARG-609 AND TRP-622;
Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.
Sato H.; Tanaka M.; Takino T.; Inoue M.; Seiki M.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 94-669; VARIANT ARG-609;
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