Variant position: 641 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1019 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VLARGGFKANFTTGYHLGIP EPCKADHFQCKNGECVPLVNL
Mouse ETRRKGFKANFTSGYYLGIP EPCQDDEFQCKDGNCIPLGNL
Pig ALTKGGFKANFTTGYHLGIP EPCKEDNFQCENGECVLLVNL
Bovine MLAKQGFKANFTTGYGLGIP EPCKEDNFQCKDGECIPLVNL
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 784 Enteropeptidase non-catalytic heavy chain
48 – 1019 Extracellular
641 – 679 LDL-receptor class A 2
630 – 630 N-linked (GlcNAc...) asparagine
No reference for the current variant in UniProtKB/Swiss-Prot.
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