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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P41180: Variant p.Pro951Thr

Extracellular calcium-sensing receptor
Gene: CASR
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Variant information Variant position: help 951
Type of variant: help LB/B
Residue change: help From Proline (P) to Threonine (T) at position 951 (P951T, p.Pro951Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 951
Protein sequence length: help 1078
Location on the sequence: help KQQQPLALTQQEQQQQPLTL P QQQRSQQQPRCKQKVIFGSG
Residue conservation: help 
Human                         KQQQPLALTQ---QEQQQQPLTL-PQQQRSQQQPRCKQKVIFGSG

Mouse                         KQQQPLALTQ---QEQQQQPLTLQPQQQQQPQQPRCKQKVI

Rat                           KQQQPLSLTQ---QEQQQQPLTLHPQQQQQPQQPRCKQKVI

Pig                           KKQQPLALTQ---HVPQPQAPSTPQPQPQLQQQPRCKQKVI

Bovine                        KQPQPLALSPHNAQQPQPRPPSTPQPQPQSQQPPRCKQKVI
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 1078 Extracellular calcium-sensing receptor
Topological domain 863 – 1078 Cytoplasmic
Region 892 – 963 Disordered



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.