Sequence information
Variant position: 157 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 509 The length of the canonical sequence.
Location on the sequence:
SGVPGGGHQREKRGWTMPGT
L WCGVGDSAGNSSELGVFQGP
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SGVPGGGHQREKRGWTMPGTL WCGVGDSAGNSSELGVFQGP
Mouse SGAPDREHRRRRRGWTIPGTL WCGVGNSAENASELGVFHGP
Bovine NGVPGIGRQWVKRGWTVPGTL WCGVGDSAGNSSELGVFQGP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
20 – 509
Group 3 secretory phospholipase A2
Region
150 – 291
Phospholipase A2-like
Metal binding
158 – 158
Calcium; via carbonyl oxygen
Metal binding
160 – 160
Calcium; via carbonyl oxygen
Metal binding
162 – 162
Calcium; via carbonyl oxygen
Glycosylation
167 – 167
N-linked (GlcNAc...) asparagine
Mutagenesis
167 – 167
N -> S. Loss of glycosylation.
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.