Variant position: 110 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 423 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human PFTIEVKANTYEKYWPFYQK QGGHYFPKDHLKKAVAEIEEM
Mouse PFTVEVKANTYEKYWPFYQK NGGLYFPKDHLKKAVAEVEEM
Rat PFTVEVKANTYEKYWPFYQK NGGLYFPKDHLKKAVAEVEEM
Pig PFTVEVKANTYEKYWPFYQK YGGHYFPKDHLKKAVAEIEEM
Bovine PFTVEVKANTYDKHWPFYQK YGGSYFPKDHLQKAVAEIEEM
Chicken PFSVEVKANTYEKYWGFYQK FGGESFPKDHVKKAIAEIEEM
Xenopus laevis PFSVEVKANTYEKYWPFYQK HGGQSFPVDHVKKAIEEIEEM
Xenopus tropicalis PFSVEVKANTYEKYWPFYQK HGGQSFPVEHVKKATEEIEEM
Zebrafish PFTVEVKANTYEKYWPFYQQ YGGQTFPKEHVQKAVAEIEEM
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
38 – 423 Glycine amidinotransferase, mitochondrial
104 – 110
Totoki Y.; Toyoda A.; Takeda T.; Sakaki Y.; Tanaka A.; Yokoyama S.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); VARIANT HIS-110;
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