Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P51825: Variant p.Pro209Ala

AF4/FMR2 family member 1
Gene: AFF1
Feedback?
Variant information Variant position: help 209
Type of variant: help LB/B
Residue change: help From Proline (P) to Alanine (A) at position 209 (P209A, p.Pro209Ala).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to small size and hydrophobic (A)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 209
Protein sequence length: help 1210
Location on the sequence: help VTDSAPERELSPLISLPSPV P PLSPIHSNQQTLPRTQGSSK
Residue conservation: help 
Human                         VTDSAPERELSPLI-SLPSPVPPLSPIHSNQQTLPRTQGSSK

Mouse                         -----PERKLSPLISSLPSPVPPLSPVHS------RLQGTS

Caenorhabditis elegans        ------YTKYHPAVEPLDCPV--------------------
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1210 AF4/FMR2 family member 1
Region 73 – 314 Disordered
Modified residue 199 – 199 Phosphoserine
Modified residue 206 – 206 Phosphoserine
Modified residue 212 – 212 Phosphoserine
Modified residue 220 – 220 Phosphothreonine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.