Sequence information
Variant position: 20 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 418 The length of the canonical sequence.
Location on the sequence:
MLYLEDYLEMIEQLPMDLR
D RFTEMREMDLQVQNAMDQLE
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Mouse MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Rat MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Chicken MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Xenopus laevis MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Xenopus tropicalis MLYLEDYLEMIEQLPMDLRD RFTEMREMDLQVQNAMDQLE
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
1 – 418
Inhibitor of growth protein 3
Literature citations
Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.
Gunduz M.; Ouchida M.; Fukushima K.; Ito S.; Jitsumori Y.; Nakashima T.; Nagai N.; Nishizaki K.; Shimizu K.;
Oncogene 21:4462-4470(2002)
Cited for: VARIANT HNSCC GLY-20;
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.