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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P17655: Variant p.Glu521Gln

Calpain-2 catalytic subunit
Gene: CAPN2
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Variant information Variant position: help 521
Type of variant: help LB/B
Residue change: help From Glutamate (E) to Glutamine (Q) at position 521 (E521Q, p.Glu521Gln).
Physico-chemical properties: help Change from medium size and acidic (E) to medium size and polar (Q)
BLOSUM score: help 2
Other resources: help


Sequence information Variant position: help 521
Protein sequence length: help 700
Location on the sequence: help VFSEKKADYQAVDDEIEANL E EFDISEDDIDDGFRRLFAQL
Residue conservation: help 
Human                         VFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQL

Mouse                         VFSEKKADYQAVDDEIEANIEEIDANEEDIDDGFRRLFVQL

Rat                           VFSEKKADYQTVDDEIEANIEEIEANEEDIGDGFRRLFAQL

Bovine                        VFSEKKADYQVVDDEIEANIDEIDISEDDIDDGFRRLFAQL

Chicken                       VFSEKNANSTVIDDEIEANFEETEIDEDDIEPSFKKLFGQL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 700 Calpain-2 catalytic subunit
Region 515 – 529 Linker



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS GLU-22; GLY-68; ARG-476; GLN-521; GLN-568 AND GLN-677;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.