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UniProtKB/Swiss-Prot Q5JSP0: Variant p.Val275Ile

FYVE, RhoGEF and PH domain-containing protein 3
Gene: FGD3
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Variant information Variant position: help 275
Type of variant: help LB/B
Residue change: help From Valine (V) to Isoleucine (I) at position 275 (V275I, p.Val275Ile).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 275
Protein sequence length: help 725
Location on the sequence: help DRAVGLVSTWTQRSPLFKDV V HSIQKQEVCGNLTLQHHMLE
Residue conservation: help 
Human                         DRAVGLVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLE

Mouse                         DRAMGLVSTWTQRSPQFKDVIHTIQKQEVCGNLTLQHHMLE
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 725 FYVE, RhoGEF and PH domain-containing protein 3
Domain 157 – 341 DH



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); VARIANT ILE-275;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.