Sequence information
Variant position: 863 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1393 The length of the canonical sequence.
Location on the sequence:
VGHSVAAQISNNMTEKKFSQ
T VLGADSEALTDSWEALSLDT
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VGHSVAAQ---ISNNMTEKKFSQT VLGADSE--ALTDSWEALSLDT
Mouse VGHSVAAQ---MSSGATDKKFSQM ELDADAE--ALTDSWEA
Rat VGHSVAAQ---MSSSATDKKFSQM VLDADAE--ALTDSWEA
Caenorhabditis elegans ICWCARIQIRILKGNDEDEVENDH DLEEEDEKNKTIDEWDA
Drosophila VCKTVATN---LWRNRKEGSCDES SQNEDDE------RWER
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
1 – 1393
Rab3 GTPase-activating protein non-catalytic subunit
Alternative sequence
207 – 1393
Missing. In isoform 2.
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.