Sequence information
Variant position: 5 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 559 The length of the canonical sequence.
Location on the sequence:
MSAC
R SFAVAICILEISILTAQYTT
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human MSACR SFAVAICILEISILTAQYTT
Mouse MASGM AITLALAIFALGVNAQMPIP
Rat MASGV TITLAIAIFALEINAQAPEP
Bovine MSAGQ RFAFAICILEISLLRAGPTP
Rabbit MAASH SFAFVVCVLEIGALTAGPTP
Horse MSAGR TFAFAICILEVSVLTAGPTP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Signal peptide
1 – 21
Literature citations
The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.
Hofsteenge J.; Blommers M.; Hess D.; Furmanek A.; Miroshnichenko O.;
J. Biol. Chem. 274:32786-32794(1999)
Cited for: GLYCOSYLATION AT TRP-48 AND TRP-51;
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.