Variant position: 2066 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 3169 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human RSRKTDPPSADAGTDYVGIS RNLDFAPGVNMQPVRVVILDD
Mouse RSRKTESLSADAGTDYVGIS RNLDFAPGVNMQTVRVVILDD
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
47 – 3169 FRAS1-related extracellular matrix protein 2
47 – 3113 Extracellular
1997 – 2103 Calx-beta 3
The full-ORF clone resource of the German cDNA consortium.
Bechtel S.; Rosenfelder H.; Duda A.; Schmidt C.P.; Ernst U.; Wellenreuther R.; Mehrle A.; Schuster C.; Bahr A.; Bloecker H.; Heubner D.; Hoerlein A.; Michel G.; Wedler H.; Koehrer K.; Ottenwaelder B.; Poustka A.; Wiemann S.; Schupp I.;
BMC Genomics 8:399-399(2007)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1910-3169 (ISOFORM 1); VARIANTS CYS-2066; SER-2153 AND ILE-2326;
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