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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9UHC1: Variant p.Tyr720Cys

DNA mismatch repair protein Mlh3
Gene: MLH3
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Variant information Variant position: help 720
Type of variant: help LB/B
Residue change: help From Tyrosine (Y) to Cysteine (C) at position 720 (Y720C, p.Tyr720Cys).
Physico-chemical properties: help Change from large size and aromatic (Y) to medium size and polar (C)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 720
Protein sequence length: help 1453
Location on the sequence: help GSKKSQTDCILSDTSPSFPW Y RHVSNDSRKTDKLIGFSKPI
Residue conservation: help 
Human                         GSKKSQTDCILSDTSPSFPWYRHVSNDSRKTDKLIGFSKPI

Baker's yeast                 -------GCRINNSTINYEKIKNIRIDGQKSR---------
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1453 DNA mismatch repair protein Mlh3



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS GLY-93; SER-120; GLN-231; ILE-420; VAL-492; GLN-600; PRO-606; GLN-624; CYS-647; CYS-720; ILE-723; PHE-741; HIS-797; ASP-826; LEU-844; GLY-845; ILE-942; PRO-966; ASN-1073; GLU-1105; ASP-1163 AND ARG-1319;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.