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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P56748: Variant p.Thr129Ala

Claudin-8
Gene: CLDN8
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Variant information Variant position: help 129
Type of variant: help LB/B
Residue change: help From Threonine (T) to Alanine (A) at position 129 (T129A, p.Thr129Ala).
Physico-chemical properties: help Change from medium size and polar (T) to small size and hydrophobic (A)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 129
Protein sequence length: help 225
Location on the sequence: help GDNEKVKAHILLTAGIIFII T GMVVLIPVSWVANAIIRDFY
Residue conservation: help 
Human                         GDNEKVKAHILLTAGIIFIITGMVVLIPVSWVANAIIRDFY

Mouse                         GDDENVKSRILLTAGIIFFITGLVVLIPVSWVANSIIRDFY
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 225 Claudin-8
Transmembrane 118 – 138 Helical



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.