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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9BZZ2: Variant p.Val221Met

Sialoadhesin
Gene: SIGLEC1
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Variant information Variant position: help 221
Type of variant: help LB/B
Residue change: help From Valine (V) to Methionine (M) at position 221 (V221M, p.Val221Met).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 221
Protein sequence length: help 1709
Location on the sequence: help TLHMAMSWQDHGRILRCQLS V ANHRAQSEIHLQVKYAPKGV
Residue conservation: help 
Human                         TLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGV

Mouse                         TLHMALSWQDHGRTLLCQFSLGAHSSRKEVYLQVPHAPKGV

Pig                           TLHMALSWQDHGRILSCQVSAAERRMQKEIHLQVQHAPKGV
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 1709 Sialoadhesin
Topological domain 20 – 1641 Extracellular
Domain 139 – 233 Ig-like C2-type 1



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.