Variant position: 314 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 516 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GPRASGNLIPQEKIVNLVND IFGAGFDTVTTAISWSLMYLV
Mouse NYKDNGGLIPEEKIVNIVND IFGAGFDTVTTAITWSILLLV
Rat NYKDNGGLIPQEKIVNIVND IFGAGFETVTTAIFWSILLLV
Rabbit NSKANSGLIPQEKIVNLVND IFGAGFDTITTALSWSLMYLV
Cat GSRANGGRIPHEKIVSLIND IFGAGFDTVTTAISWSLMYLV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Sequence of a new human cytochrome P450-1A2 cDNA.
Zhuge J.; Qian Y.; Xie H.; Yu Y.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT VAL-314;
Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.
Solus J.F.; Arietta B.J.; Harris J.R.; Sexton D.P.; Steward J.Q.; McMunn C.; Ihrie P.; Mehall J.M.; Edwards T.L.; Dawson E.P.;
Cited for: VARIANTS CYS-18; ARG-298; VAL-314 AND TRP-431;
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