Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P48637: Variant p.Arg236Gln

Glutathione synthetase
Gene: GSS
Feedback?
Variant information Variant position: help 236
Type of variant: help LB/B
Residue change: help From Arginine (R) to Glutamine (Q) at position 236 (R236Q, p.Arg236Gln).
Physico-chemical properties: help Change from large size and basic (R) to medium size and polar (Q)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 236
Protein sequence length: help 474
Location on the sequence: help NIFDQRAIENELLARNIHVI R RTFEDISEKGSLDQDRRLFV
Residue conservation: help 
Human                         NIFDQRAIENELLAR-NIHVIRRTFEDISEKGSLDQDRR--LFV

Mouse                         NIFDQRAVENELLDR-KIHVIRGRFEDVSERGSLDQNRR--

Rat                           NIFDQRAIENELLDR-KIHVIRRRFEDVSERGSLDQNRR--

Bovine                        NIFDQRAIENELLAR-NIHVIRRKFEDVSEKGSLDQDRR--

Xenopus laevis                NILDQRFIEAELCKR-NVRVIRRRLADVFERGTLDEERH--

Slime mold                    NIYDQKGLEFQLWSNHSIKLIRRTMKEINQCAKLDEENGSV

Baker's yeast                 NVFDQKVLELNLLEKFGTKSVRLTFDDVNDKLFIDDKTGK-

Fission yeast                 NITDQRTLEYELLNRFHVISKRIDIAELNS-LIHDKSSNK-
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 474 Glutathione synthetase
Binding site 220 – 220
Beta strand 234 – 237



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS GLN-236 AND GLU-437;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.