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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q05469: Variant p.Lys497Asn

Hormone-sensitive lipase
Gene: LIPE
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Variant information Variant position: help 497
Type of variant: help LB/B
Residue change: help From Lysine (K) to Asparagine (N) at position 497 (K497N, p.Lys497Asn).
Physico-chemical properties: help Change from large size and basic (K) to medium size and polar (N)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 497
Protein sequence length: help 1076
Location on the sequence: help AIRPFLQTISIGLVSFGEHY K RNETGLSVAASSLFTSGRFA
Residue conservation: help 
Human                         AIRPFLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFA

Mouse                         AIRPFLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFA

Rat                           AIRPFLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFA

Pig                           AIRPFLQTISIGLVSFGEHYKRNETGLSVTASSLFTSGRFA

Bovine                        AIRPFLQTISIGLVSFGEHYKRNETGISVTASSLFTDGRFA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1076 Hormone-sensitive lipase



Literature citations
Submission
SeattleSNPs variation discovery resource;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS HIS-100; HIS-127; SER-146; THR-177; VAL-194; GLN-217; ASN-497; HIS-499 AND SER-938;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.