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UniProtKB/Swiss-Prot P59796: Variant p.Gln58His

Glutathione peroxidase 6
Gene: GPX6
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Variant information Variant position: help 58
Type of variant: help LB/B
Residue change: help From Glutamine (Q) to Histidine (H) at position 58 (Q58H, p.Gln58His).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and polar.
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 58
Protein sequence length: help 221
Location on the sequence: help GTIYEYGALTLNGEEYIQFK Q FAGKHVLFVNVAAYUGLAAQ
Residue conservation: help 
Human                         GTIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYXGLAAQ

Mouse                         GTVYEYGANTIDGGEFVNFQQYAGKHILFVNVASFCGLTAT

Rat                           GTVYEYGANTLDGGEYVQFQQYAGKHILFVNVASFCGLTAT
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 221 Glutathione peroxidase 6
Active site 73 – 73
Non 73 – 73 Selenocysteine



Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS LEU-6; LEU-13; HIS-53; HIS-58; ASN-72; ASP-136; MET-140; SER-157; GLY-161 AND ALA-188;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.