Variant position: 57 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 475 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human FHVALLGGTAELLCPLSLWP GTVPKEVRWLRSPFPQRSQAV
Mouse VYIAPLRDTANLPCPLFLWP NMVLSEMRWYRPGHLPRTQAV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
30 – 475 Erythroid membrane-associated protein
30 – 155 Extracellular
30 – 140 Ig-like V-type
50 – 126
Scianna antigens including Rd are expressed by ERMAP.
Wagner F.F.; Poole J.; Flegel W.A.;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE SC-3); POLYMORPHISM; VARIANTS BLOOD GROUP SC2 ARG-57 AND SC4 ALA-60; VARIANT TYR-26;
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