Variant position: 1213 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1663 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human IIIILENLEKSSLSELLRDF LAPLENRSTESPCTFQKGNGL
Gorilla IIIILENLEKSSLSELLRDF LAPLENRSTESPCTFQKGNGL
Mouse IIVILENLEKSSLSELLGDF LAPLENRSTESPCTFQKGNGT
Rat IIVILENLEKSSLSELLGDF LAPLENRSTESPCTFQKGNGT
Rabbit IIIILENLENSSLSELLGDF LAPLENRSTESPCTFQKGNGA
Sheep IIIILENLEKSSLSELLGDF LGPLENHSTESPCTFQKGNGM
Cat IIIILENLEKSSLSELLGDF LAPLENRSTESPWTFQKGNGT
Horse IIIILENLERSSLSELLGDF LAPLENRCPESPCTFQKGNGT
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1663 Cortactin-binding protein 2
Identification of the human cortactin-binding protein-2 gene from the autism candidate region at 7q31.
Cheung J.; Petek E.; Nakabayashi K.; Tsui L.-C.; Vincent J.B.; Scherer S.W.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT VAL-1213; TISSUE SPECIFICITY;
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