Sequence information
Variant position: 309 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 374 The length of the canonical sequence.
Location on the sequence:
SVVVGVAASGEEIATRPFQL
V TGRTWKGTAFGGWKSVESVP
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SVVVGVAASGEEIATRPFQLV TGRTWKGTAFGGWKSVESVP
Mouse SVVVGVAASGEEISTRPFQLV TGRTWKGTAFGGWKSVESVP
Rat SVVVGVAASGEEISTRPFQLV TGRTWKGTAFGGWKSVESVP
Bovine SVVVGVAASGEEIATRPFQLV TGRTWKGTAFGGWKSVESVP
Rabbit SVVVGVAGAGEEISTRPFQLV TGRTWKGTAFGGWKSVESVP
Horse SVVVGVAASGEEIATRPFQLV TGRTWKGTAFGGWKSVESIP
Caenorhabditis elegans SCIIGVAGAGQEIATRPFQLV TGRTWKGTAFGGWKSVESVP
Drosophila SVVIGVAGAGQEISTRPFQLV VGRVWKGSAFGGWRSVSDVP
Slime mold STIVGVAPAGAEISTRPFQLV TGRVWKGSAFGGVKSRSQLP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
2 – 374
Alcohol dehydrogenase class-3
Modified residue
315 – 315
N6-succinyllysine
Modified residue
324 – 324
Phosphoserine
Helix
306 – 309
Literature citations
Submission
NIEHS SNPs program;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS SER-163 AND ILE-309;
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.