Variant position: 102 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1054 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GELEAFIQNLNLAKYTKASL VEEDEPAEKENSSKKEVKIPK
Mouse GELESFIQNLNLAKYSK-SL IEEDEPEKKENASKKEAKLLK
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1054 CCAAT/enhancer-binding protein zeta
102 – 160 Disordered
102 – 123 Basic and acidic residues
113 – 113 Phosphoserine
A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter.
Lum L.; Sultzman L.; Kaufman R.; Linzer D.I.H.; Wu B.;
Mol. Cell. Biol. 10:6709-6717(1990)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT ILE-102;
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
Zhou H.; Di Palma S.; Preisinger C.; Peng M.; Polat A.N.; Heck A.J.; Mohammed S.;
J. Proteome Res. 12:260-271(2013)
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-629 AND SER-959; VARIANT [LARGE SCALE ANALYSIS] ILE-102; IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];
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