Variant position: 1511 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 2320 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human KTSAGISSGVTSGDSSDSAE SSERRKRNRP--ITNGSTLSESE
Mouse KTSAGVSSGFTSGDSSDSAG SLERVRRQRPEVLRSGSVLFG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 2320 Bromodomain and WD repeat-containing protein 1
1434 – 1593 Disordered
121 – 2320 Missing. In isoform D.
Isolation and characterization of a new chromosome 21 gene, WDR9, with different alternatively spliced transcripts and different protein forms.
Scott H.S.; Barras C.; Mittaz L.; Michaud J.; Guidi S.; Scamuffa N.; Antonarakis S.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B); VARIANTS PRO-1511 AND PRO-1699;
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