Variant position: 342 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1156 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SKGFGHIWLDSVSCQGHEPA IWQCKHHEWGKHYCNHNEDAG
Mouse SEGSGQIWLDNISCEGHEAT LWECKHQEWGKHYCHHREDAG
Pig SEGTGHIWLDSVSCHGHESA LWQCRHHEWGKHYCNHDEDAG
Bovine SEGTGHIWLDSVSCQGHESA VWQCRHHEWGKHYCNHNEDAG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.
Law S.K.A.; Micklem K.J.; Shaw J.M.; Zhang X.-P.; Dong Y.; Willis A.C.; Mason D.Y.;
Eur. J. Immunol. 23:2320-2325(1993)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4); VARIANT VAL-342;
Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily.
Ritter M.; Buechler C.; Langmann T.; Schmitz G.;
Biochem. Biophys. Res. Commun. 260:466-474(1999)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANT VAL-342;
Scavenger receptor cd163 is a cell permissive factor for infection with porcine reproductive and respiratory syndrome viruses.
Welch S.-K.W.; Calvert J.G.; Slade D.E.; Shields S.L.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3); VARIANT VAL-342;
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); VARIANT VAL-342;
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