Variant position: 551 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 720 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GGQSVTMGYYKNEAKTKADF FEDENGQRWLCTGDIGEFEPD
Mouse GGQNVTMGYYKNEAKTKTDF FEDENGQRWLCTGDIGEFDPD
Rat GGQNVTMGYYKNEAKTKADF FEDENGQRWLCTGDIGEFDPD
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 720 Long-chain-fatty-acid--CoA ligase 3
42 – 720 Cytoplasmic
Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35.
Minekura H.; Fujino T.; Kang M.-J.; Fujita T.; Endo Y.; Yamamoto T.T.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT SER-551;
Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene.
Minekura H.; Kang M.-J.; Inagaki Y.; Suzuki H.; Sato H.; Fujino T.; Yamamoto T.T.;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]; VARIANT SER-551;
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