Variant position: 747 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 818 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human LLHFPLVNASFKDHSAPGVQ RSPAELQGGQVDLTGATCPYT
Mouse VLHFPLVNDSFRDHSAPGVR RSPDELKAGQVNLTGAASPYF
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 818 Cytosolic phospholipase A2 delta
273 – 818 PLA2c
724 – 818 Missing. In isoform 2.
A family based study of the genetic association between the PLA2G4D gene and schizophrenia.
Tao R.; Yu Y.; Zhang X.; Shi J.; Guo Y.; Wang C.; Han B.; Xu Q.; Shang H.; Zhang X.; Xie L.; Liu S.; Ju G.; Shen Y.; Wei J.;
Prostaglandins Leukot. Essent. Fatty Acids 73:419-422(2005)
Cited for: VARIANT GLY-747;
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