Variant position: 1523 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1704 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SWGLTAYSEKHHWHLCCDSS RTQTEWMTSIFIAQHEYDIWP
Mouse SWGLTVYSEKHHWHLCCDSL QAQMEWMASIFIAQHENDIWP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1704 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
1434 – 1537 PH 5
ARAP1: a point of convergence for Arf and Rho signaling.
Miura K.; Jacques K.M.; Stauffer S.; Kubosaki A.; Zhu K.; Hirsch D.S.; Resau J.; Zheng Y.; Randazzo P.A.;
Mol. Cell 9:109-119(2002)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; TISSUE SPECIFICITY; VARIANT GLN-1523;
Wong J.A.; Chen Z.; Marignani P.A.; Yu M.; Zhao Y.; Vallis K.A.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT GLN-1523;
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
Nagase T.; Ishikawa K.; Miyajima N.; Tanaka A.; Kotani H.; Nomura N.; Ohara O.;
DNA Res. 5:31-39(1998)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 74-1704; VARIANT GLN-1523;
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