Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P33151: Variant p.Ile503Thr

Cadherin-5
Gene: CDH5
Feedback?
Variant information Variant position: help 503
Type of variant: help LB/B
Residue change: help From Isoleucine (I) to Threonine (T) at position 503 (I503T, p.Ile503Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (I) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 503
Protein sequence length: help 784
Location on the sequence: help YQPKVCENAVHGQLVLQISA I DKDITPRNVKFKFILNTENN
Residue conservation: help 
Human                         YQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFILNTEN-N

Mouse                         YEPKVCENAAQGKLVVQISATDKDVVPVNPKFKFALKNEDS

Pig                           YEAKVCEDAPQGKLVVQISAIDKDVTPRDVKFKFSLSTEDS

Bovine                        YEPKVCENAPQGKLVVQISATDKDITPRDVKFKFSLSTEDS

Chicken                       EEPRVCENAAPGKVIIRISATDKDEISPGGFFTYSLTTEDS

Zebrafish                     SYVYVCENDKPNTIIGTIGASDKDENS--GRFRFTLARKSS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 48 – 784 Cadherin-5
Topological domain 48 – 599 Extracellular
Domain 478 – 593 Cadherin 5
Glycosylation 523 – 523 N-linked (GlcNAc...) asparagine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.