Sequence information
Variant position: 68 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 136 The length of the canonical sequence.
Location on the sequence:
GFEPADNKCLLRATDGKKKI
S TVVSSKEVNKFQMAYSNLLR
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GFEPADNKCLLRATDG----KKKIS TVVSSKEVNKFQMAYSNLLR
GFEPSDNKCLLRATDG----KKKIS TVVSSKEVNKFQMAYS
Mouse GLEPAENKCLLRATDG----KRKIS TVVSSKEVNKFQMAYS
Bovine GFEPSDNKCLLRATDG----KKKIS TVVSSKEVNKFQMAYS
Caenorhabditis elegans EGDEIS--CIFRAKWG----SKKIA TEVKAKEVNKFHTQYS
Slime mold ESEEEENKCLVRATNG----KKKIS TIVLAKDKSMFEKNYK
Baker's yeast SRSDREYPLLIRMSYGSHDKKTKCS TVVKASELDQFWQEYS
Fission yeast EGEGSSASVLIRAKSGA---AEKIS TVVELDYFTDFFQSYA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
2 – 136
Signal recognition particle 14 kDa protein
Beta strand
53 – 72
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.