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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q13421: Variant p.Ala72Val

Mesothelin
Gene: MSLN
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Variant information Variant position: help 72
Type of variant: help LB/B
Residue change: help From Alanine (A) to Valine (V) at position 72 (A72V, p.Ala72Val).
Physico-chemical properties: help Change from small size and hydrophobic (A) to medium size and hydrophobic (V)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 72
Protein sequence length: help 630
Location on the sequence: help LANPPNISSLSPRQLLGFPC A EVSGLSTERVRELAVALAQK
Residue conservation: help 
Human                         LANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQK

Mouse                         -NGAADFASLPTGLFLGLTCEEVSDLSMEQAKGLAMAVRQK

Rat                           -TGTVDFASLPTGLFLGLMCDEVSGLSMGHAKELAMAVRQK
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 37 – 606 Mesothelin
Chain 37 – 286 Megakaryocyte-potentiating factor
Glycosylation 57 – 57 N-linked (GlcNAc...) asparagine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.