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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q96J65: Variant p.Lys894Met

ATP-binding cassette sub-family C member 12
Gene: ABCC12
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Variant information Variant position: help 894
Type of variant: help LB/B
Residue change: help From Lysine (K) to Methionine (M) at position 894 (K894M, p.Lys894Met).
Physico-chemical properties: help Change from large size and basic (K) to medium size and hydrophobic (M)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 894
Protein sequence length: help 1359
Location on the sequence: help TKTTLMASSSLHDTVFDKIL K SPMSFFDTTPTGRLMNRFSK
Residue conservation: help 
Human                         TKTTLMASSSLHDTVFDKILKSPMSFFDTTPTGRLMNRFSK

Mouse                         TNTTLMASSSLHNRVFNKIVRSPMSFFDTTPTGRLMNRFSK

Rat                           TNTTLMASSSLHNRVFNKIVSSPMSFFDTTPTGRLMNRFSK
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1359 ATP-binding cassette sub-family C member 12
Domain 795 – 1082 ABC transmembrane type-1 2
Alternative sequence 634 – 1359 Missing. In isoform 4.
Alternative sequence 892 – 938 ILKSPMSFFDTTPTGRLMNRFSKDMDELDVRLPFHAENFLQQFFMVV -> HFPQRSPGAQEGGECQPVTLVHPHHLLHAGPGHHSRLWQEGELHHLV. In isoform 3.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.