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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P04114: Variant p.Val4394Ala

Apolipoprotein B-100
Gene: APOB
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Variant information Variant position: help 4394
Type of variant: help LB/B
Residue change: help From Valine (V) to Alanine (A) at position 4394 (V4394A, p.Val4394Ala).
Physico-chemical properties: help Change from medium size and hydrophobic (V) to small size and hydrophobic (A)
BLOSUM score: help 0
Polymorphism: help Genetic variations in APOB define the low density lipoprotein cholesterol level quantitative trait locus 4 (LDLCQ4) [MIM:615558].
Other resources: help


Sequence information Variant position: help 4394
Protein sequence length: help 4563
Location on the sequence: help LQQIHQYIMALREEYFDPSI V GWTVKYYELEEKIVSLIKNL
Residue conservation: help 
Human                         LQQIHQYIMALREEYFDPSIVGWTVKYYELEEKIVSLIKNL

Mouse                         LQQVHQYMKALREEYFDPSMVGWTVKYYEIEENMVELIKTL

Rat                           LQQVHQYMKAFREEYFDPSVVGWTVKYYEIEEKMVDLIKTL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 28 – 4563 Apolipoprotein B-100



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.