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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9UI33: Variant p.Met777Arg

Sodium channel protein type 11 subunit alpha
Gene: SCN11A
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Variant information Variant position: help 777
Type of variant: help LB/B
Residue change: help From Methionine (M) to Arginine (R) at position 777 (M777R, p.Met777Arg).
Physico-chemical properties: help Change from medium size and hydrophobic (M) to large size and basic (R)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 777
Protein sequence length: help 1791
Location on the sequence: help SFLVVFRILCGEWIENMWEC M QEANASSSLCVIVFILITVI
Residue conservation: help 
Human                         SFLVVFRILCGEWIENMWECMQEANASSSLCVIVFILITVI

Mouse                         SFLVVFRILCGEWIENMWECMQEMEG-SPLCVIVFVLIMVV

Rat                           SFLVVFRILCGEWIENMWGCMQDMDG-SPLCIIVFVLIMVI
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1791 Sodium channel protein type 11 subunit alpha
Topological domain 775 – 785 Extracellular
Repeat 559 – 833 II
Glycosylation 781 – 781 N-linked (GlcNAc...) asparagine
Disulfide bond 776 – 787



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.