Variant position: 170 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 560 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human LAALWFPEHQRATANMLATM SNPLGVLVANVLSPVLVKKGE
Mouse LAALWFPEHQRATANMISTM SNPLGLLIANVLSPALVKKAD
Xenopus tropicalis LASVWFPEHQRATANMIASM SNPLGVLLANIISPSVVTKEE
Zebrafish LAALWFPDHQRATANMLASM ANTVGLLLANLLSPLIVSYSG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 560 Solute carrier family 49 member A3
166 – 186 Helical
99 – 195 Missing. In isoform 3.
No reference for the current variant in UniProtKB/Swiss-Prot.
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