Variant position: 2979 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 3907 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SLTESPYSDGEDHSIQQVSE PWLEERKAYINTISSLKDLIT
Mouse SLSSPLCDDGEDRSIQQLSE SWLKERQAYLNTISSLKDLIS
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 3907 A-kinase anchor protein 9
1625 – 3900 Missing. In isoform 4.
Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the Golgi apparatus.
Takahashi M.; Shibata H.; Shimakawa M.; Miyamoto M.; Mukai H.; Ono Y.;
J. Biol. Chem. 274:17267-17274(1999)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3); VARIANTS ILE-463 AND SER-2979;
AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes.
Schmidt P.H.; Dransfield D.T.; Claudio J.O.; Hawley R.G.; Trotter K.W.; Milgram S.L.; Goldenring J.R.;
J. Biol. Chem. 274:3055-3066(1999)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 311-3907 (ISOFORM 2); NUCLEOTIDE SEQUENCE [MRNA] OF 2145-3907 (ISOFORM 6); SUBCELLULAR LOCATION; VARIANT SER-2979;
Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T.; Ishikawa K.; Suyama M.; Kikuno R.; Miyajima N.; Tanaka A.; Kotani H.; Nomura N.; Ohara O.;
DNA Res. 5:277-286(1998)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2200-3907 (ISOFORMS 2/3); VARIANT SER-2979;
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