Variant position: 185 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 570 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SECSVVERTIPVCRESRRKR KSYIVMSPESPVKCGTQTSSP
Mouse SECSAVERTIPVCRESRRKR KSYIVMSPESPVKCSTQTSSP
Rat SECSAVERTIPVCRESRRKR KSYIVMSPESPVKCSTQTNSP
Xenopus tropicalis SECSVVERTIPICRESRRKR KSYIVMSPESPLKCNTQTSSP
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 570 Zinc finger and BTB domain-containing protein 44
165 – 165 Phosphoserine
191 – 191 Phosphoserine
194 – 194 Phosphoserine
200 – 200 Phosphothreonine
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 4); VARIANT GLU-185;
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