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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O75581: Variant p.Ser817Cys

Low-density lipoprotein receptor-related protein 6
Gene: LRP6
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Variant information Variant position: help 817
Type of variant: help LB/B
Residue change: help From Serine (S) to Cysteine (C) at position 817 (S817C, p.Ser817Cys).
Physico-chemical properties: help Change from small size and polar (S) to medium size and polar (C)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 817
Protein sequence length: help 1613
Location on the sequence: help TIDYAKRRLYWTDLDTNLIE S SNMLGLNREVIADDLPHPFG
Residue conservation: help 
Human                         TIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFG

Mouse                         TIDYAKRRLYWTDLDTNLIESSDMLGLNREVIADDLPHPFG
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 20 – 1613 Low-density lipoprotein receptor-related protein 6
Topological domain 20 – 1370 Extracellular
Repeat 803 – 842 LDL-receptor class B 14
Region 631 – 890 Beta-propeller 3
Beta strand 814 – 819



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.