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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P80108: Variant p.Asp275Glu

Phosphatidylinositol-glycan-specific phospholipase D
Gene: GPLD1
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Variant information Variant position: help 275
Type of variant: help LB/B
Residue change: help From Aspartate (D) to Glutamate (E) at position 275 (D275E, p.Asp275Glu).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and acidic.
BLOSUM score: help 2
Other resources: help


Sequence information Variant position: help 275
Protein sequence length: help 840
Location on the sequence: help AFWSTNIYHLTSFMLENGTS D CNLPENPLFIACGGQQNHTQ
Residue conservation: help 
Human                         AFWSTNIYHLTSFMLENGTSDCNLPENPLFIACGGQQNHT-Q

Mouse                         AFWSTNIYRLTSFMLENGTSDCNLPENPLFISCDGR-NHTL

Rat                           AFWSTNIYRLTSFMLENGTSDCNLPENPLFISCDGRKNHTL

Bovine                        AFWSTNIYHLTSYMLKNGTSNCNLPENPLFITCGGQQNNT-
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 24 – 840 Phosphatidylinositol-glycan-specific phospholipase D
Glycosylation 271 – 271 N-linked (GlcNAc...) asparagine
Glycosylation 292 – 292 N-linked (GlcNAc...) asparagine
Alternative sequence 177 – 840 Missing. In isoform 2.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.