Variant position: 84 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 91 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ILIILCVMAGIIGTILLISY SIRRLIKA
Chimpanzee ILIILCVMAGVIGTILLISY GIRLLIKA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
20 – 91 Glycophorin-B
82 – 91 Cytoplasmic
Molecular cloning of a human glycophorin B cDNA: nucleotide sequence and genomic relationship to glycophorin A.
Siebert P.D.; Fukuda M.;
Proc. Natl. Acad. Sci. U.S.A. 84:6735-6739(1987)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); VARIANT THR-84;
Structural organization of glycophorin A and B genes: glycophorin B gene evolved by homologous recombination at Alu repeat sequences.
Kudo S.; Fukuda M.;
Proc. Natl. Acad. Sci. U.S.A. 86:4619-4623(1989)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANT THR-84;
The low-incidence MNS antigens M(v), s(D), and Mit arise from single amino acid substitutions on GPB.
Storry J.R.; Reid M.E.; MacLennan S.; Lubenko A.; Nortman P.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); VARIANT M(V) SER-22; VARIANTS MIT MET-48 AND HIS-54; VARIANT S(D) ARG-58; VARIANT THR-84;
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.