Variant position: 111 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 299 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ENLTEEDAGTYWCGVDTPWL RDF--HDPVVEVEVSVFPASTSM
Mouse ESLTLEDADTYMCAVDISLF DGSLGFDKYFKIELSVVPSED
Rat QNLTLEDAGTYMCAVDIPLI DHS------FKVELSVVPGNI
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
18 – 299 CMRF35-like molecule 8
18 – 180 Extracellular
19 – 123 Ig-like V-type
92 – 92 N-linked (GlcNAc...) asparagine
14 – 209 Missing. In isoform 3.
14 – 126 Missing. In isoform 2 and isoform 4.
Cantoni C.; Biassoni R.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3); VARIANT GLN-111;
Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility.
Speckman R.A.; Wright Daw J.A.; Helms C.; Duan S.; Cao L.; Taillon-Miller P.; Kwok P.Y.; Menter A.; Bowcock A.M.;
Hum. Genet. 112:34-41(2003)
Cited for: VARIANT GLN-111;
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