Variant position: 156 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 296 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human AAETAKELTPFLLKSKILSP NGGKPKAINQEMFKLSSMDVT
Mouse SSETIKKLFPSLLDTKNLST GSGKPKAIDQDKFKLSSLDVV
Rat VSETVRKLFPSLLDTKNLSP GSGKPKAINQEMFKLSSLDVT
Bovine ASETIKELTPSLLDVKNLPV GDGKPKAIDPEMFKLSSVDPS
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 296 Glycine N-acyltransferase
141 – 141 N6-acetyllysine; alternate
141 – 141 N6-succinyllysine; alternate
159 – 159 N6-acetyllysine
169 – 169 N6-succinyllysine
163 – 163 I -> M. In isoform 2.
The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase.
van der Westhuizen F.H.; Pretorius P.J.; Erasmus E.;
J. Biochem. Mol. Toxicol. 14:102-109(2000)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2); VARIANT SER-156;
Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.
Matsuo M.; Terai K.; Kameda N.; Matsumoto A.; Kurokawa Y.; Funase Y.; Nishikawa K.; Sugaya N.; Hiruta N.; Kishimoto T.;
Biochem. Biophys. Res. Commun. 420:901-906(2012)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); FUNCTION; CATALYTIC ACTIVITY; SUBCELLULAR LOCATION; TISSUE SPECIFICITY; VARIANT SER-156;
Kishimoto T.; Niwa S.; Nishikawa K.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); VARIANT SER-156;
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2); VARIANTS THR-17 AND SER-156;
Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201).
Ebert L.; Schick M.; Neubert P.; Schatten R.; Henze S.; Korn B.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-163; VARIANT SER-156;
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